Gene Information
NCBI Gene ID 842669
Symbol EGL3
LocusTag AT1G63650
Synonyms ATMYC-2|EGL1|ENHANCER OF GLABRA3|F24D7.16|F24D7_16
Description EGL3 (ENHANCER OF GLABRA3); DNA binding
Gene Type protein-coding
Pattern EGL3|AT1G63650|ATMYC-2|EGL1|ENHANCER OF GLABRA3|F24D7.16|F24D7_16|EGL3 (ENHANCER OF GLABRA3); DNA binding|EGL3 (ENHANCER OF GLABRA3); DNA binding / transcription factor
Corresponding sequence in Trichome EST library AF505625 AI489467 AM827767 AW735767 BF647387 BF650729 BI308638 BI928114 BP897984 DB682225 DB689218 DB700583 DB702617 DB722533 DB727170 FG622526 FS188920 FS197585 GO604805 GO607910 TCSL81490 


SAD2 in Arabidopsis functions in trichome initiation through mediating GL3 function and regulating GL1, TTG1 and GL2 expression.
Gao Y, Gong X, Cao W, Zhao J, Fu L, Wang X, Schumaker KS, Guo Y. J Integr Plant Biol. 2008 Jul;50(7):906-17

...... resulting in reduced trichome number, but had no effect on trichome development or root hair number and development. Expression levels of GL1, MYB23, GL2 and TTG1 were reduced in shoots of sad2 mutants while expression levels of GL3 and ENHANCER OF GLABRA3 (EGL3) were enhanced. Overexpression of GL3 increased trichome numbers in wild type but not in sad2 mutants, indicating that the function of the GL3 protein is altered in the sad2 mutants. In contrast, overexpression of GFP-GL1 decreased ......

Comprehensive analysis of single-repeat R3 MYB proteins in epidermal cell patterning and their transcriptional regulation in Arabidopsis.
Wang S, Hubbard L, Chang Y, Guo J, Schiefelbein J, Chen JG. BMC Plant Biol. 2008 Jul 21;8:81

...... formation on cotyledons and siliques, organs that normally do not bear any trichomes. By using Arabidopsis protoplast transfection assays, we found that all single-repeat R3 MYBs examined interact with GL3, and that GL1 or WER and GL3 or EGL3 are required and sufficient to activate the transcription of TRY, CPC, ETC1 and ETC3, but not TCL1 and ETC2. Furthermore, only ETC1's transcription was greatly reduced in the gl3 egl3 double mutants. CONCLUSION: Our comprehensive analysis ......

A network of redundant bHLH proteins functions in all TTG1-dependent pathways of Arabidopsis.
Zhang F, Gonzalez A, Zhao M, Payne CT, Lloyd A. Development. 2003 Oct;130(20):4859-69.

...... suppresses the trichome defect of the pleiotropic ttg1 mutations. However, single gl3 mutations only affect the trichome pathway with a modest trichome number reduction. A novel unlinked bHLH-encoding locus is described here, ENHANCER OF GLABRA3 (EGL3). When mutated, egl3 gives totally glabrous plants only in the gl3 mutant background. The double bHLH mutant, gl3 egl3, has a pleiotropic phenotype like ttg1 having defective anthocyanin production, seed coat mucilage production, and ......